Activities

Activities:

• Development of investigation protocols and informed patient consent forms;
• Comprehensive revision of literature data;
• Training in microbiological research methodology.

Activities:

• Recruitment of eligible patients for the treatment study group;
• Recruitment of eligible patients for the study control group;
• Recruitment of eligible individuals for the healthy control group;
• Diagnosis of ankylosing spondylitis by patient compliance ASAS criteria for classification of spondyloarthritis;
• Collect biological material (stool samples) for intestinal microbiome research.

• Activities:
  • Sample processing and storage;
  • Microbial DNA extraction;
  • Preparation;
  • Library sequencing;
  • Analysis of composition of microbiota.

Activities:

• Correlating gut microbiome data with the degree of AS activity;
• Interrelationship between gut microbiome particularities in AS patients and BASDAI scores;
• Determination of high-risk microbiome variants for severe evolution of AS;
• Evaluation of microbiome composition with protective effect against severe evolution of AS.

Activities:

• Presentation of data during seminars;
• Publication of original research articles in national and international specialized journals.